Kim H. Esbensen’s impact as a world leader within representative sampling (Theory of Sampling, TOS), Process Analytical Technology (PAT) and Chemometrics (multivariate data analysis) is demonstrated in his CV, describing a professional career spanning 35 years in academe with a distinct international scope (~250 publications, ~400 lectures/presentations). His university teaching experience covers chemometrics, PAT and TOS, Instrumental analysis, Multivariate Image Analysis (MIA) and Philosophy of Science. He has founded and led three academic research groups, supervised ~60 M.Sc. and 15 Ph.D. theses. He has served as opponent at 25 Ph.D. defences. He organised and chaired two international chemometrics conferences (1990 and 1999), and served as Editor of the Proceedings of the latter (SSC6). He founded the World Conference on Sampling and Blending (WCSB), which is now in its 7.th edition; he was the inaugural chairman of WCSB1 (2003), Denmark and co-chairman of WCSB7 (2015), France; he served as Editor for the Proceedings at both these conferences. He has founded TOS forum, an international scientific and communication forum for the world sampling community. He chaired the taskforce responsible for the world’s first horizontal (matrix-independent) standard for representative sampling, DS 3077 (2013). From 2010 new application fields include GMO, food & feed. He is the principal scientist for an EU project on “Representative sampling for GM plant risk assessment” (OC/EFSA/GMO/2013/04) and he organised the taskforce responsible for the J. AOAC. Int. Special Guest Editor section: “Representative Sampling for food and Feed Materials” (2015). He has visited and lectured at many international research groups and university institutes and has given numerous dedicated courses (TOS, PAT, chemometrics) to major international companies, organisations, regulatory bodies and agencies. From 2015 he has re-established close collaboration with CAMO, a world-leading chemometrics company a.o. as responsible for the 7.th revised edition of his hugely successful textbook (33.000 copies, 2001-2015).
Esbensen recently started a phased transition from academe to an international consultancy, KHE Consulting, combined with visiting professorships, offering a broad suite of lectures/seminar topics as well as compact, dedicated Ph.D. level courses intended both for academe and industry; for Ph.D. students these courses are accredited at three universities. Esbensen continues as adjunct professor at Aalborg University, campus Esbjerg and at the Geological Survey of Denmark and Greenland (GEUS).
Educational outreach: courses (academe courses, or dedicated for companies, agencies, other)
- Introduction to the Theory and Practise of Representative Sampling (TOS) (5 ECTS)
- Introduction to Chemometrics (multivariate Data analysis and modelling) (5 ECTS)
- Process Analytical Technology (PAT): TOS meets Chemometrics meets PAT (10 ECTS)
Educational activity is offered at university level (Ph.D. & M.Sc.) as compact courses (3-4-5 full-day duration/content) equivalent to 5 or 10 ECTS. Comprehensive, up-to-date curriculum literature is included. Course plans are developed in collaboration with clients’ wishes.
Educational outreach: lecture/seminar themes (1, or 2 x 45 minutes)
- Why we need the unique Theory of Sampling (TOS)
- Materials and Processes: Heterogeneity and appropriate sampling modes
- DS 3077 Horizontal: Representative sampling - a new international standard
- Theory of Sampling (TOS) vs Measurement Uncertainty (MU)
- Process Sampling (1-D TOS) – the missing link in process analytical technology (PAT)
- Representative sampling for food and feed materials: TOS is essential Distributional assumptions in food and feed commodities (incl. the KeLDA study)
- The Theory of Sampling at the interface between field and the analytical laboratory
- Introducing TOS and variographic characterisation in process monitoring and QC
- Proper sampling, total measurement uncertainty, variographic analysis & fit-for-purpose acceptance levels for pharmaceutical mixing monitoring
- Multivariate data analysis (chemometrics) in science, technology & industry
- Proper Validation: use and abuse of re-sampling for data model validation
- Representative sampling, data quality, validation – a necessary trinity in process analytical technology application
- Five years in a governmental institution – lessons learned (not all bad ;-))
Selected literature, lectures and promotional documentation:
- Esbensen, K.H, Wagner, C. (2014) Theory of Sampling (TOS) versus Measurement Uncertainty (MU) – a call for integration. Trends in Analytical Chemistry (TrAC), vol 57, pp. 93-106
- DS 3077 (2013) Esbensen, K.H. (chairman taskforce F-205 2008-2013). “DS 3077. Representative sampling – Horizontal Standard”. Danish Standards. www.ds.dk
- Esbensen, K.H. & Mortensen, P. (2010). Process Sampling (Theory of Sampling, TOS) – the Missing Link in Process Analytical Technology (PAT). in Bakeev, K. A. (Ed.) Process Analytical Technology. 2.nd Edition. pp. 37-80. Wiley. ISBN 978-0-470-72207-7
- Esbensen, K.H. & Julius, L.P. (2009). Representative sampling, data quality, validation – a necessary trinity in chemometrics. in Brown, S, Tauler, R, Walczak,R (Eds.) COMPREHENSIVE CHEMOMETRICS, Wiley Major Reference Works, vol. 4, pp.1-20. Oxford
- Esbensen, K.H, Romanach, R.J. (2015) Proper sampling, total measurement uncertainty, variographic analysis & fit-for-purpose acceptance levels for pharmaceutical mixing monitoring. TOS forum, Issue 5. pp 25-30. Doi: 10.1255/tosf.68
- Esbensen, K.H. (2015) Process Measurement System QC/QA – the missing link in MSPC (whitepaper)
- Esbensen, K.H, Paoletti, C, Theix, N. (2015) (Eds) Journal AOAC International, Special Guest Editor Section (SGE): Sampling for Food and Feed Materials. pp. 249-320 http://ingentaconnect.com/content/aoac/jaoac/2015/00000098/00000002
- Esbensen, K.H, Wagner, C. (2015) (Eds) Proceedings 7.th World Conference on Sampling and Blending (WCSB7) June 10-12, 2015. Bordeaux. TOS forum Issue No 5. 238 p. IM Publishers, Chichester. ISSN 2053-9681 www.impublications.com/wcsb7
- Esbensen, K.H., Paoletti, C. & Minkkinen, P. (2012). Representative sampling of large kernel lots – I. Theory of Sampling and variographic analysis. Trends in Analytical Chemistry (TrAC), 32 pp.154-165 doi:10.1016/j. trac.2011.09.008
- Minkkinen, P., Esbensen, K.H. & Paoletti, C. (2012). Representative sampling of large kernel lots – II. Application to soybean sampling for GMO control. Trends in Analytical Chemistry (TrAC), 32 pp. 166-178 xx. doi:10.1016/j.trac.2011.12.001
- Esbensen, K.H., Paoletti, C. & Minkkinen, P. (2012). Representative sampling of large kernel lots – III. General Considerations on sampling heterogeneous foods. Trends in Analytical Chemistry (TrAC), 32 pp. 179-184 doi:10.1016/j.trac.2011.12.002
- Holm-Nielsen, J.B. & K.H. Esbensen (2011). Monitoriong of Biogas Test Plants – A Process Analytical Technology Approach. Journal of Chemometrics, Special Issue: “WSC-7: 7th Winter Symposium on Chemometrics”, vol. 25, Issue 7, p. 357–365, July 2011. doi: 10.1002/cem.1344
- Esbensen, K.H. & Geladi, P. (2010). Principles of Proper Validation: use and abuse of re-sampling for validation. Journal of Chemometrics, vol 24, 168-187. (www.interscience.wiley.com) DOI: 10.1002/cem.1310
- Esbensen, K.H. & Geladi, P. (2009). Principal Component Analysis (PCA): Concept, geometrical interpretation, mathematical background, algorithms, history. in Brown, S, Tauler, R, Walczak, R (Eds.) COMPREHENSIVE CHEMOMETRICS, Wiley Major Reference Works, vol. 4, pp 211-226. Elsevier.
- Esbensen, K.H., Halstensen, M., Lied, T.L., Saudland, A., Svalestuen, J., de Silva, S. & Hope B. (1998): Acoustic chemometrics - from noise to information. Chemometrics and Intel. Lab. Systems, 44, 61-76.
- Selinus, O.S. & Esbensen, K.H. (1995): Separating anthopogenic from natural anomalies in environmental geochemistry. Jour. Geochem. Explor., 55, 55-66.